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Diabetes is one of the major causes of death in the US, and it exists in different types. These include the Diabetes type 1 and type 2. These two make the most commonly experienced forms of diabetes. This hinders the diagnosis process given that there is an absence of tools which can serve to create a distinction between the different types of diabetes. Consequently, the intervention process was mired in confusion. This is because all types of diabetes share a majority of the symptoms with insignificant disparities. [“Write my essay for me?” Get help here.]

Diabetes results in gives rise to several complications in the body. Some of the health complications that can be triggered by this disease include heart attacks and strokes. The high content of sugar in the blood poses a potential danger to the heart (Vaziri-Sani, et al., 2010). Both diabetes 1 and 2 can also result in breathing problems. The excessive presence of glucose in the blood causes an osmotic imbalance, which may affect the flow of oxygen in the body. In addition, it also impedes the transportation of carbon dioxide outside of the body. Likewise, diabetes can lead to kidney failure given the excessive accumulation of unconverted glucose in the blood. Several risk factors such as family history of the disease, smoking, age, and lack of exercise can trigger make people get this disease.

The prevailing need for the development of a diagnostic tool that could differentiate these types of diabetes resulted in the creation of the ZnT8Ab autoantibody assay tool. This diagnostic tool is used in the testing phases of diabetes. It is used with the intention of distinguishing the type 1 and type 2 diabetes in patients. It achieves this objective through the assessment of the presence of the ZnT8Ab autoantibodies in the human body. The presence of the antibodies is indicative of the presence of diabetes type 1 (Vaziri-Sani, et al., 2010). Essentially, individuals with the other types of diabetes do not produce the autoantibodies which serves as a distinctive framework between the types of diabetes. [Need an essay writing service? Find help here.]

Type 1 diabetes interferes with the body metabolism of the victims. In the type 1 diabetes, insulin-producing cells in the pancreas are attacked by the immune system. Insulin plays a vital role in the human body metabolism. It converts sugar, which is found in consumed food into energy and used by the body. The regulation of glucose in the blood is a demanding and necessary process given that the entire body processes are influenced by the amount of sugar present in the blood.  [Need an essay writing service? Find help here.]

The article FDA allows marketing of first ZnT8Ab autoantibody test to help diagnose type 1 diabetes alludes to the impact that the ZnT8Ab autoantibody assay will have the distinction of diabetes 1 and diabetes 2 components. The identification of Diabetes type 1 in the infant stages allows for the prevention of the destruction of insulin-producing cells. The insulin-producing cells release chemical components which regulate the amount of sugar that is present in the body. This, in turn, curtails the propagation of Diabetes in the body. Early identification of the Diabetes 1 in the early stages further enables an early diagnosis, which enhances the chances of the success of the engaged intervention. [Click Essay Writer to order your essay]

The US Drug & Food Association (2014) prevails that the ZnT8Ab autoantibody serves to identify the presence of the ZnT8Ab autoantibodies in the body. This enables the physicians to create a distinction between the different types of diabetes. The review of the ZnT8Ab autoantibody assay diagnostic tool was conducted through the de novo premarket review pathway. The de novo pathway is often engaged in the assessment of testing and diagnostic tools that project a low-to-middle risk potential (Department of Health and Human Services, 2014).

In sanctioning the diagnostic framework, the US Drug & Food Association (2014) engaged population samples. The development of the ZnT8Ab autoantibody tool involved the testing of 569 blood samples (Department of Health and Human Services, 2014). The blood samples were taken from individuals who suffered diabetes. 323 patients were diagnosed with diabetes type 1. The diabetes type 1 was marked by the presence of the ZnT8Ab autoantibodies in the bodies of the patients. The autoantibodies were identified through the employ of the ZnT8Ab assay tool. Of the total sample number, 246 of the blood samples were devoid of the ZnT8Ab autoantibodies. This succinctly shows that there is a disparity between diabetes 1 and diabetes 2 despite the shared symptoms. The ZnT8Ab autoantibody assay tool is mostly efficient in children and young adults.

Diabetes 1 affects children more than it does the adults. Children between the ages of 3 to 15 years project a higher risk of developing diabetes. Studies show that 80 percent of individuals between this age group project the presence of the ZnT8Ab autoantibodies in their blood (Vaziri-Sani, et al., 2010). The success of the ensuing interventions is subject to how early the intervention was instituted. The earlier the intervention, the more likely it is that the patient will be rescued before diabetes affects them significantly. Earlier intervention results in efficient results in children more than is the same for the adults. However, the employ of the ZnT8Ab tool levels the possibilities of intervention success in both the children and the adults. The ZnT8Ab autoantibody assay tool projects an error of 2%. Essentially, when the test indicates the absence of the ZnT8Ab, it does not completely rule out the presence of diabetes 1 in the diabetic patient.

In conclusion, the use of the ZnT8Ab autoantibodies assay tool can lead to the development of titters, known as the ZnT8Ab titters. However, as one grows up and the disease progresses in the body, the titters reduce significantly. The reduction is further enhanced by the early intervention of diabetes type 1. Early intervention is achieved with the ZnT8Ab autoantibody assay tool.


Vaziri-Sani, F., Oak, S., Ratke, J., Lernmark, A., Lynch, K., Agardh, C. D., . . .Hampe, C. S. (2010). ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset. Autoimmunity, 43(8), 598-606.

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By Hanna Robinson

Hanna has won numerous writing awards. She specializes in academic writing, copywriting, business plans and resumes. After graduating from the Comosun College's journalism program, she went on to work at community newspapers throughout Atlantic Canada, before embarking on her freelancing journey.

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